An intensive course in the principles of modern aspects of toxicology, taught in a lecture/case study format.
Advanced topics in toxicology will include oral presentations by students, faculty members, and guest lecturers. The emphasis will be on advanced concepts and techniques in toxicology research with particular relevance to mechanistic, molecular and interpretive toxicology. Offered in conjunction with TOX*4200. Extra work is required of graduate students.
The molecular mechanisms of action of carcinogens and other toxic compounds. Enzymes of biotransformation, including a detailed study of cytochrome P-450. Interactions of reactive species with DNA and other macromolecules. Offered in conjunction with TOX*4590. Extra work is required of graduate students.